Dosing

HOW TRODELVY IS GIVEN

TRODELVY® (sacituzumab govitecan-hziy) Dosing intravenous icon

TRODELVY is an intravenous (IV) infusion (10 mg/kg)

TRODELVY® (sacituzumab govitecan-hziy) dosing calendar icon

Doses are given once a week for 2 weeks (Day 1 and Day 8) of 21-day treatment cycles

TRODELVY® (sacituzumab govitecan-hziy) treatment cycles icon

Each treatment cycle is 21 days (3 weeks)

sample 21-day treatment cycle

TRODELVY® (sacituzumab govitecan-hziy) sample 21-day treatment cycle calendar

Treatment cycles repeat every 21 days

You and your healthcare provider will decide how many treatment cycles you receive. This may be based on factors such as whether your tumor has responded to treatment or your body’s ability to tolerate treatment.

sample 21-day treatment cycle

TRODELVY® (sacituzumab govitecan-hziy) sample 21-day treatment cycle calendar

Treatment cycles repeat every 21 days

You and your healthcare provider will decide how many treatment cycles you receive. This may be based on factors such as whether your tumor has responded to treatment or your body’s ability to tolerate treatment.

WHAT TO EXPECT ON TREATMENT DAYS

Your healthcare provider may recommend the following on treatment days:

  • Your weight measured to find the right dose
  • A short physical exam to check your blood pressure, pulse, breathing, and temperature
  • An IV tube put in your arm
  • A blood sample taken

On treatment days, you can also expect to go through these 3 steps:

1
PRE-INFUSION

You may be given medicines before your infusion to help prevent infusion reactions, including a fever reducer, antihistamines, or corticosteroids. Your healthcare provider may also give you medicine to help reduce or prevent nausea or vomiting.

2
INFUSION

Your first infusion will take approximately 3 hours. Your healthcare provider will observe you during the infusion.

After that, if prior treatment was well tolerated, your infusions with TRODELVY may take 1 to 2 hours.

3
OBSERVATION

After each infusion, your healthcare provider will watch you for reactions for at least 30 minutes.

If you experience any side effects while taking TRODELVY, tell your healthcare provider right away. Please read the Important Safety Information below and the information on Side Effects.

Your healthcare provider may give you medicines to take home that can help you manage the side effects of TRODELVY. Keep track of when and how often side effects occur, as well as their severity, so your healthcare provider can best support you.

Before starting TRODELVY, tell your healthcare provider about any medicines you are taking. Be sure to include prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines may affect the way TRODELVY works.