Side Effects

SIDE EFFECTS: WHAT YOU MAY EXPECT

It's important to understand what side effects may be expected with TRODELVY, including serious side effects. Contact your healthcare provider immediately if you experience any side effects. Some side effects may require medical attention and, for some side effects, your healthcare provider may have tips to help you manage or cope with them.

The most common side effects seen in ≥25% of all patients were:

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Nausea

Nausea

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Diarrhea

Diarrhea

 
TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: feeling tired

Feeling tired

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Decreased white blood cell count

Decreased white blood cell count (neutropenia)

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Hair Loss

Hair loss

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Diarrhea

Decreased red blood cell count (anemia)

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Nausea

Vomiting

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Decreased red blood cell count

Constipation

 
TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: feeling tired

Decreased appetite

TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: feeling tired

Rash

 
TRODELVY® (sacituzumab govitecan-hziy) Side effects icon: Hair Loss

Stomach-area (abdominal) pain or discomfort

TRODELVY can also cause serious side effects, including low white blood cell counts called neutrophils (neutropenia), severe diarrhea, serious infusion-related reactions and severe allergic reactions that can be life-threatening, and nausea.

  • Serious side effects occurred in 44% of patients receiving TRODELVY. The most common serious side effects in ≥5% of patients in the TRODELVY group were infection (18%), low white blood cell counts called neutrophils (12%), acute kidney injury (6%), urinary tract infections (6%), and blood infections (5%)

Be sure to tell your healthcare provider about any side effects you have while on TRODELVY. They may be able to help by:

  • Recommending medications that support your treatment
  • Reducing/interrupting your dose
  • Discontinuing your treatment with TRODELVY
2% of patients stopped treatment due to side effects

These are not all of the possible side effects of TRODELVY. Tell your healthcare provider about any side effects that bother you or do not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.